Early postoperative
pelvic-floor biofeedback improves
erectile
function in men undergoing radical prostatectomy: a prospective, randomized,
controlled trial.
Source
Division of Urology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil.
Abstract
Erectile dysfunction (ED) and urinary incontinence are common complications
following radical prostatectomy (RP). Although pelvic-floor
biofeedback training (PFBT) may improve urinary continence
following RP, its effects on the recovery of potency are unknown.
Fifty-two patients selected for RP were prospectively randomized for a
treatment group (n=26) receiving PFBT once a week for 3 months and home
exercises or a control group (n=26), in which patients
received verbal instructions to contract the pelvic floor.
Erectile
function (EF) was evaluated with the International Index of
Erectile
Function-5
(IIEF-5) before surgery and 1, 3, 6 and 12 months postoperatively.
Patients were considered potent when
they had a total IIEF-5 score>20. Continence status was assessed and
defined as the use of no pads. Groups were comparable in terms of age,
body mass index, diabetes, pathological tumor stage and neurovascular
bundle preservation. A significant reduction in
IIEF-5 scores was observed after surgery in both groups. In the
treatment group, 8 (47.1%) patients recovered potency 12 months
postoperatively, as opposed to 2 (12.5%) in the control group (P=0.032).
The absolute risk reduction was 34.6% (95% confidence interval
(CI): 3.8-64%) and the number needed to treat was 3 (95% CI: 1.5-17.2).
A strong association between recovery of potency and urinary continence
was observed, with continent patients having a 5.4 higher chance of
being potent (P=0.04). Early PFBT appears to
have a significant impact on the recovery of EF after RP. Urinary
continence status was a good indicator of EF recovery, with continent
patients having a higher chance of being potent.
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